KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FIP1L1
All Species:
24.55
Human Site:
T539
Identified Species:
67.5
UniProt:
Q6UN15
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UN15
NP_001128409.1
594
66526
T539
R
H
R
E
K
E
E
T
R
H
K
S
S
R
S
Chimpanzee
Pan troglodytes
XP_001147016
603
67380
T548
R
H
R
E
K
E
E
T
R
H
K
S
S
R
S
Rhesus Macaque
Macaca mulatta
XP_001090808
594
66538
T539
R
H
R
E
K
E
E
T
R
H
K
S
S
R
S
Dog
Lupus familis
XP_853955
764
84414
T709
R
H
R
E
K
E
E
T
R
H
K
S
S
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9D824
581
64940
T526
R
H
R
E
K
E
E
T
R
H
K
S
S
R
S
Rat
Rattus norvegicus
Q5U317
536
60169
R482
H
R
E
K
E
E
T
R
H
K
S
S
R
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517022
711
77022
S646
Y
N
K
Y
E
L
F
S
S
H
P
S
L
P
F
Chicken
Gallus gallus
XP_001233386
773
84522
T718
R
H
R
E
K
E
D
T
R
H
K
S
S
R
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5XJD3
570
62947
R512
R
H
G
G
R
R
H
R
E
K
E
E
G
R
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
99.8
73.5
N.A.
93.5
87.7
N.A.
26.5
62.7
N.A.
53.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.5
99.8
75.9
N.A.
94.4
88.3
N.A.
37.1
68.5
N.A.
66.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
13.3
N.A.
13.3
93.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
33.3
N.A.
40
100
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
12
67
23
78
56
0
12
0
12
12
0
0
0
% E
% Phe:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
12
% F
% Gly:
0
0
12
12
0
0
0
0
0
0
0
0
12
0
0
% G
% His:
12
78
0
0
0
0
12
0
12
78
0
0
0
0
12
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
12
12
67
0
0
0
0
23
67
0
0
0
0
% K
% Leu:
0
0
0
0
0
12
0
0
0
0
0
0
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
12
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
12
0
0
12
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
78
12
67
0
12
12
0
23
67
0
0
0
12
78
0
% R
% Ser:
0
0
0
0
0
0
0
12
12
0
12
89
67
12
67
% S
% Thr:
0
0
0
0
0
0
12
67
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
12
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _